Elabscience

SKU: PKSH031522_50μg-ES

Recombinant Human TCN2 Protein (His Tag), 50 μg (PKSH031522)

Transcobalamin II, also known as TCN2 and TC II, is a plasma protein that binds cobalamin (Cbl; vitamin B12) as it is absorbed in the terminal ileum and distributes to tissues. The circulating transcobalamin II-cobalamin complex binds to receptors on the plasma membrane of tissue cells and is then internalized by receptor-mediated endocytosis. Transcobalamin II is a non-glycolated secretory protein of molecular mass 43 kDa. Its plasma membrane receptor (TC II-R) is a heavily glycosylated protein with a monomeric molecular mass of 62 kDa. Human TCN2 gene is composed of nine exons and eight introns spanning approximately 20 kb with multiple potential transcription start sites. A number of genetic abnormalities are characterized either by a failure to express TCN2 or by synthesis of an abnormal protein. The TCN2 deficiency results in cellular cobalamin deficiency, an early onset of megaloblastic anaemia, and neurological abnormalities.

HK$1,020.00
HK$1,020.00
2-4 Weeks
Hassle-Free Warranty
Safe & Secure Payment
Livetime Tech Support
  • Specification
  • Downloads
  • Reviews
$1,020.00
ADD TO CART
ADD TO CART

Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

Warranty:

Safety Performance:

Protection Class:

Sterile Status:

Reconstitution:Please refer to the printed manual for detailed information.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Battery:

Battery Service Life:

Component:

Technical Specifications

Capacity:

Concentration:

Dimension [D×W×H]:

Diameter:

Length:

Width:

High:

Volume:

Volume Range:

Speed:

Speed Range:

Max.Speed:

Max. RCF:

Temperature Range:

Operating Temperature Range:

Permissible Ambient Temperature :

Permissible Relative Humidity:

Input voltage:

Power Requirements:

Voltage/Frequency:

Sensitivity:

Specificity:

Precision:

Speed Accuracy:

Volume Accuracy:

Particle Size:

Pore Size:

Binding Capacity:

Calculated Molecular Weight:46.7 kDa

Observed Molecular Weight:43 kDa

Purity: > 90 % as determined by reducing SDS-PAGE.

Shelf Life:

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Random Error:

Acceleration/Braking time:

Aspiration Speed:

Calculated Molecular Weight:46.7 kDa

Dilution:

Driving Motor DC motor:

Em:

Ex:

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Flow rate [liquid]:

Features and Capabilities

Application:ELISA

Detection Target:

Detection Type:

Detection Range:

Research Areas:Signal Transduction;Cardiovascular;metabolism;

Species Reactivity:

Reactivity:

Target Synonym:

Test Principle:

Quantitative/Qualitative :

Result Type:

Materials :

Assay Time:

Autoclave component:

Available Rotor Adapters:

Binding Capacity:

Bio-activity:Immobilized human TCN2-His at 10μg/mL (100μL/well) can bind biotinylated mouse CD320-His. The EC50 of biotinylated mouse CD320-His is 18-42 ng/mL.

Bottom Shape:

Bottom Type:

Buffer:

Cap Color:

Clonality:

Conjugation:

Coupled Ligand:

Cover Type:

Detection Instrument :

Dispensing Speed:

Display:

Form:

Formulation:Lyophilized from sterile PBS, pH 7.4
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Graduation:

Growth Area:

Download File