Elabscience

SKU: E-AB-F1381H_100T×2-ES

PE/Cyanine7 Anti-Human CD158b/j Antibody[DX27], 100 T×2

CD158b is expressed on natural killer cells and a subset of T cells. It is a member of the immunoglobulin superfamily containing two immunoglobulin C2-type domains. Both variants and alternative isoforms of CD158b have been reported. The interaction of CD158b with specific HLA-C antigens on a target cell (HLA-Cw1, HLA-Cw3, HLA-Cw7 alleles, for example) inhibits cytotoxicity and prevents target cell lysis and death. The interactions between KIR and MHC class I are thought to be important in NK cell and T cell regulation following antigen stimulation. The absence of ligands for KIRs may lower the threshold for activation through activating receptors and increase inflammation and susceptibility to autoimmune disease.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Concentration:5μL/Tests

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Shelf Life:12 months

Storage:This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

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Clonality:Monoclonal

Conjugation:PE/Cyanine 7

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