Elabscience

Artikelnummer: E-AB-81534_100μL-ES

Recombinant Axin 2 Monoclonal Antibody, 100 μL

The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.

HK$312.00
HK$312.00
2-4 Weeks
Hassle-Free Warranty
Safe & Secure Payment
Livetime Tech Support
  • Specification
  • Downloads
  • Reviews
$312.00
ADD TO CART
ADD TO CART

Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

Warranty:

Safety Performance:

Protection Class:

Sterile Status:

Reconstitution:

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Battery:

Battery Service Life:

Component:

Technical Specifications

Capacity:

Concentration:300 μg/mL

Dimension [D×W×H]:

Diameter:

Length:

Width:

High:

Volume:

Volume Range:

Speed:

Speed Range:

Max.Speed:

Max. RCF:

Temperature Range:

Operating Temperature Range:

Permissible Ambient Temperature :

Permissible Relative Humidity:

Input voltage:

Power Requirements:

Voltage/Frequency:

Sensitivity:

Specificity:

Precision:

Speed Accuracy:

Volume Accuracy:

Particle Size:

Pore Size:

Binding Capacity:

Calculated Molecular Weight:94kDa

Observed Molecular Weight:94kDa

Purity:

Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Random Error:

Acceleration/Braking time:

Aspiration Speed:

Calculated Molecular Weight:94kDa

Dilution:WB 1:500-1:1000

Driving Motor DC motor:

Em:

Ex:

Endotoxin:

Flow rate [liquid]:

Features and Capabilities

Application:WB

Detection Target:

Detection Type:

Detection Range:

Research Areas:Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Neuroscience; Stem Cells

Species Reactivity:Human; Mouse; Rat

Reactivity:

Target Synonym:AXIN2;AXIL;ODCRCS;axin-2

Test Principle:

Quantitative/Qualitative :

Result Type:

Materials :

Assay Time:

Autoclave component:

Available Rotor Adapters:

Binding Capacity:

Bio-activity:

Bottom Shape:

Bottom Type:

Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Cap Color:

Clonality:Rabbit Monoclonal

Conjugation:Unconjugated

Coupled Ligand:

Cover Type:

Detection Instrument :

Dispensing Speed:

Display:

Form:

Formulation:

Graduation:

Growth Area:

Download File