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Artikelnummer: E-BC-K884-M_96T-ES
NETosis Colorimetric Assay Kit, 96T
NETosis is an inflammatory cell death mode of neutrophils. Activated neutrophils capture and kill pathogens by releasing Neutrophil extracellular traps (NETs), which are composed of deaggregated chromatin and intracellular granule proteins. The formation of NETs is accompanied by the death of neutrophils. This new type of death is different from apoptosis and necrosis and is called NETosis. There are many inducers of NETosis, such as pathogens (bacteria, fungi, viruses, etc.), activated platelets, chemokines (interleukins, granulocyte colony-stimulating factor, transforming growth factor β, etc.), artificial ingredients and calcium ionophore, etc. These inducers can promote the key proteins of NETosis, Neutrophil Elastase (NE), Myeloperoxidase (MPO) and Peptidearginine Deaminase IV (PAD4) transcription and translation.
This method evaluated the degree of NETosis by detecting the enzyme activity of NE.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shipping:Ice bag
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Sensitivity:0.31 U/L
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Shelf Life:12 months
Storage:This product can be stored at -20°C for 12 months with shading light.
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Detection Type:Colorimetric method
Detection Range: 0.31-18.33 U/L
Research Areas: Metabolic Diseases
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Result Type:Quantitative
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Assay Time:7 h 20 min
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Detection Instrument :Microplate reader
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